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We present DRaWR, a network-based method for ranking genes or properties related to a given gene set. Such related genes or properties are identified from among the nodes of a large, heterogeneous network of biological information. Our method involves a random walk with restarts, performed on an initial network with multiple node and edge types, preserving more of the original, specific property information than current methods that operate on homogeneous networks. In this first stage of our algorithm, we find the properties that are the most relevant to the given gene set and extract a subnetwork of the original network, comprising only the relevant properties. We then rerank genes by their similarity to the given gene set, based on a second random walk with restarts, performed on the above subnetwork.

copied from cf-staging / r-drawr
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conda 58.7 kB | noarch/r-drawr-1.0.3-r44hc72bb7e_3.conda  7 months and 27 days ago 597 main
conda 59.0 kB | noarch/r-drawr-1.0.3-r43hc72bb7e_3.conda  7 months and 27 days ago 591 main
conda 59.1 kB | noarch/r-drawr-1.0.3-r43hc72bb7e_2.conda  1 year and 8 months ago 1048 main
conda 59.0 kB | noarch/r-drawr-1.0.3-r42hc72bb7e_2.conda  1 year and 8 months ago 1020 main
conda 59.0 kB | noarch/r-drawr-1.0.3-r42hc72bb7e_1.tar.bz2  2 years and 4 months ago 1400 main
conda 59.0 kB | noarch/r-drawr-1.0.3-r41hc72bb7e_1.tar.bz2  2 years and 4 months ago 1397 main
conda 58.4 kB | noarch/r-drawr-1.0.3-r40hc72bb7e_0.tar.bz2  2 years and 11 months ago 1974 main
conda 58.5 kB | noarch/r-drawr-1.0.3-r41hc72bb7e_0.tar.bz2  2 years and 11 months ago 1995 main

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