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conda-forge / packages / r-allelicseries

Implementation of gene-level rare variant association tests targeting allelic series: genes where increasingly deleterious mutations have increasingly large phenotypic effects. The COding-variant Allelic Series Test (COAST) operates on the benign missense variants (BMVs), deleterious missense variants (DMVs), and protein truncating variants (PTVs) within a gene. COAST uses a set of adjustable weights that tailor the test towards rejecting the null hypothesis for genes where the average magnitude of effect increases monotonically from BMVs to DMVs to PTVs. See McCaw ZR, Somineni H, Bereket M, Klein C, Karaletsos T, Casale FP, Koller D, Soare TW. (2022) "An allelic series rare variant association test for candidate gene discovery" <doi:10.1101/2022.12.23.521658>.

copied from cf-post-staging / r-allelicseries
Type Size Name Uploaded Downloads Labels
conda 151.0 kB | win-64/r-allelicseries-0.0.4.1-r43h3dc9324_1.conda  11 months and 2 days ago 167 main
conda 159.5 kB | osx-64/r-allelicseries-0.0.4.1-r44hfd06a21_1.conda  11 months and 2 days ago 97 main
conda 152.6 kB | win-64/r-allelicseries-0.0.4.1-r44h3dc9324_1.conda  11 months and 2 days ago 172 main
conda 157.9 kB | osx-64/r-allelicseries-0.0.4.1-r43hfd06a21_1.conda  11 months and 2 days ago 90 main
conda 163.8 kB | linux-64/r-allelicseries-0.0.4.1-r43hb79369c_1.conda  11 months and 2 days ago 931 main
conda 165.5 kB | linux-64/r-allelicseries-0.0.4.1-r44hb79369c_1.conda  11 months and 2 days ago 908 main
conda 157.3 kB | win-64/r-allelicseries-0.0.4.1-r41h78deb2a_0.conda  1 year and 11 months ago 350 main
conda 156.4 kB | osx-64/r-allelicseries-0.0.4.1-r43h6e7f656_0.conda  1 year and 11 months ago 208 main
conda 156.6 kB | osx-64/r-allelicseries-0.0.4.1-r42h6e7f656_0.conda  1 year and 11 months ago 208 main
conda 161.2 kB | linux-64/r-allelicseries-0.0.4.1-r43h08d816e_0.conda  1 year and 11 months ago 1730 main
conda 162.0 kB | linux-64/r-allelicseries-0.0.4.1-r42h08d816e_0.conda  1 year and 11 months ago 1726 main

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