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conda-forge / packages / r-allelicseries

Implementation of gene-level rare variant association tests targeting allelic series: genes where increasingly deleterious mutations have increasingly large phenotypic effects. The COding-variant Allelic Series Test (COAST) operates on the benign missense variants (BMVs), deleterious missense variants (DMVs), and protein truncating variants (PTVs) within a gene. COAST uses a set of adjustable weights that tailor the test towards rejecting the null hypothesis for genes where the average magnitude of effect increases monotonically from BMVs to DMVs to PTVs. See McCaw ZR, Somineni H, Bereket M, Klein C, Karaletsos T, Casale FP, Koller D, Soare TW. (2022) "An allelic series rare variant association test for candidate gene discovery" <doi:10.1101/2022.12.23.521658>.

copied from cf-staging / r-allelicseries
Type Size Name Uploaded Downloads Labels
conda 380.3 kB | win-64/r-allelicseries-0.1.1.2-r43h3dc9324_0.conda  3 months and 7 days ago 375 main
conda 376.9 kB | win-64/r-allelicseries-0.1.1.2-r44h3dc9324_0.conda  3 months and 7 days ago 341 main
conda 382.1 kB | osx-64/r-allelicseries-0.1.1.2-r44h0287f03_0.conda  3 months and 7 days ago 130 main
conda 382.2 kB | osx-64/r-allelicseries-0.1.1.2-r43h0287f03_0.conda  3 months and 7 days ago 135 main
conda 398.6 kB | linux-64/r-allelicseries-0.1.1.2-r44hb79369c_0.conda  3 months and 7 days ago 508 main
conda 402.5 kB | linux-64/r-allelicseries-0.1.1.2-r43hb79369c_0.conda  3 months and 7 days ago 532 main
conda 379.3 kB | win-64/r-allelicseries-0.1.1.1-r43h3dc9324_0.conda  3 months and 8 days ago 350 main
conda 376.8 kB | win-64/r-allelicseries-0.1.1.1-r44h3dc9324_0.conda  3 months and 8 days ago 349 main
conda 382.4 kB | osx-64/r-allelicseries-0.1.1.1-r43h0287f03_0.conda  3 months and 8 days ago 119 main
conda 382.3 kB | osx-64/r-allelicseries-0.1.1.1-r44h0287f03_0.conda  3 months and 8 days ago 140 main
conda 402.0 kB | linux-64/r-allelicseries-0.1.1.1-r43hb79369c_0.conda  3 months and 8 days ago 517 main
conda 398.5 kB | linux-64/r-allelicseries-0.1.1.1-r44hb79369c_0.conda  3 months and 8 days ago 521 main
conda 151.0 kB | win-64/r-allelicseries-0.0.4.1-r43h3dc9324_1.conda  4 months and 1 day ago 136 main
conda 159.5 kB | osx-64/r-allelicseries-0.0.4.1-r44hfd06a21_1.conda  4 months and 1 day ago 73 main
conda 152.6 kB | win-64/r-allelicseries-0.0.4.1-r44h3dc9324_1.conda  4 months and 1 day ago 140 main
conda 157.9 kB | osx-64/r-allelicseries-0.0.4.1-r43hfd06a21_1.conda  4 months and 1 day ago 71 main
conda 163.8 kB | linux-64/r-allelicseries-0.0.4.1-r43hb79369c_1.conda  4 months and 1 day ago 457 main
conda 165.5 kB | linux-64/r-allelicseries-0.0.4.1-r44hb79369c_1.conda  4 months and 1 day ago 440 main
conda 157.3 kB | win-64/r-allelicseries-0.0.4.1-r41h78deb2a_0.conda  1 year and 4 months ago 337 main
conda 156.4 kB | osx-64/r-allelicseries-0.0.4.1-r43h6e7f656_0.conda  1 year and 4 months ago 201 main
conda 156.6 kB | osx-64/r-allelicseries-0.0.4.1-r42h6e7f656_0.conda  1 year and 4 months ago 201 main
conda 161.2 kB | linux-64/r-allelicseries-0.0.4.1-r43h08d816e_0.conda  1 year and 4 months ago 1279 main
conda 162.0 kB | linux-64/r-allelicseries-0.0.4.1-r42h08d816e_0.conda  1 year and 4 months ago 1250 main
conda 157.0 kB | win-64/r-allelicseries-0.0.3.0-r41h78deb2a_1.conda  1 year and 7 months ago 431 main
conda 158.5 kB | osx-64/r-allelicseries-0.0.3.0-r43he9b8800_1.conda  1 year and 7 months ago 183 main
conda 158.7 kB | osx-64/r-allelicseries-0.0.3.0-r42he9b8800_1.conda  1 year and 7 months ago 196 main
conda 160.2 kB | linux-64/r-allelicseries-0.0.3.0-r43h08d816e_1.conda  1 year and 7 months ago 1335 main
conda 160.7 kB | linux-64/r-allelicseries-0.0.3.0-r42h08d816e_1.conda  1 year and 7 months ago 1295 main
conda 156.8 kB | win-64/r-allelicseries-0.0.3.0-r41h78deb2a_0.conda  1 year and 7 months ago 433 main
conda 158.8 kB | osx-64/r-allelicseries-0.0.3.0-r42he9b8800_0.conda  1 year and 7 months ago 181 main
conda 160.7 kB | linux-64/r-allelicseries-0.0.3.0-r42h08d816e_0.conda  1 year and 7 months ago 1297 main

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