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conda-forge / packages / r-allelicseries

Implementation of gene-level rare variant association tests targeting allelic series: genes where increasingly deleterious mutations have increasingly large phenotypic effects. The COding-variant Allelic Series Test (COAST) operates on the benign missense variants (BMVs), deleterious missense variants (DMVs), and protein truncating variants (PTVs) within a gene. COAST uses a set of adjustable weights that tailor the test towards rejecting the null hypothesis for genes where the average magnitude of effect increases monotonically from BMVs to DMVs to PTVs. See McCaw ZR, Somineni H, Bereket M, Klein C, Karaletsos T, Casale FP, Koller D, Soare TW. (2022) "An allelic series rare variant association test for candidate gene discovery" <doi:10.1101/2022.12.23.521658>.

copied from cf-staging / r-allelicseries
Type Size Name Uploaded Downloads Labels
conda 380.3 kB | win-64/r-allelicseries-0.1.1.2-r43h3dc9324_0.conda  3 months and 22 days ago 380 main
conda 376.9 kB | win-64/r-allelicseries-0.1.1.2-r44h3dc9324_0.conda  3 months and 22 days ago 345 main
conda 382.1 kB | osx-64/r-allelicseries-0.1.1.2-r44h0287f03_0.conda  3 months and 22 days ago 130 main
conda 382.2 kB | osx-64/r-allelicseries-0.1.1.2-r43h0287f03_0.conda  3 months and 22 days ago 135 main
conda 398.6 kB | linux-64/r-allelicseries-0.1.1.2-r44hb79369c_0.conda  3 months and 22 days ago 542 main
conda 402.5 kB | linux-64/r-allelicseries-0.1.1.2-r43hb79369c_0.conda  3 months and 22 days ago 569 main
conda 379.3 kB | win-64/r-allelicseries-0.1.1.1-r43h3dc9324_0.conda  3 months and 24 days ago 353 main
conda 376.8 kB | win-64/r-allelicseries-0.1.1.1-r44h3dc9324_0.conda  3 months and 24 days ago 354 main
conda 382.4 kB | osx-64/r-allelicseries-0.1.1.1-r43h0287f03_0.conda  3 months and 24 days ago 119 main
conda 382.3 kB | osx-64/r-allelicseries-0.1.1.1-r44h0287f03_0.conda  3 months and 24 days ago 140 main
conda 402.0 kB | linux-64/r-allelicseries-0.1.1.1-r43hb79369c_0.conda  3 months and 24 days ago 553 main
conda 398.5 kB | linux-64/r-allelicseries-0.1.1.1-r44hb79369c_0.conda  3 months and 24 days ago 556 main
conda 151.0 kB | win-64/r-allelicseries-0.0.4.1-r43h3dc9324_1.conda  4 months and 17 days ago 141 main
conda 159.5 kB | osx-64/r-allelicseries-0.0.4.1-r44hfd06a21_1.conda  4 months and 17 days ago 74 main
conda 152.6 kB | win-64/r-allelicseries-0.0.4.1-r44h3dc9324_1.conda  4 months and 17 days ago 145 main
conda 157.9 kB | osx-64/r-allelicseries-0.0.4.1-r43hfd06a21_1.conda  4 months and 17 days ago 71 main
conda 163.8 kB | linux-64/r-allelicseries-0.0.4.1-r43hb79369c_1.conda  4 months and 17 days ago 494 main
conda 165.5 kB | linux-64/r-allelicseries-0.0.4.1-r44hb79369c_1.conda  4 months and 17 days ago 473 main
conda 157.3 kB | win-64/r-allelicseries-0.0.4.1-r41h78deb2a_0.conda  1 year and 5 months ago 338 main
conda 156.4 kB | osx-64/r-allelicseries-0.0.4.1-r43h6e7f656_0.conda  1 year and 5 months ago 201 main
conda 156.6 kB | osx-64/r-allelicseries-0.0.4.1-r42h6e7f656_0.conda  1 year and 5 months ago 201 main
conda 161.2 kB | linux-64/r-allelicseries-0.0.4.1-r43h08d816e_0.conda  1 year and 5 months ago 1311 main
conda 162.0 kB | linux-64/r-allelicseries-0.0.4.1-r42h08d816e_0.conda  1 year and 5 months ago 1283 main
conda 157.0 kB | win-64/r-allelicseries-0.0.3.0-r41h78deb2a_1.conda  1 year and 7 months ago 432 main
conda 158.5 kB | osx-64/r-allelicseries-0.0.3.0-r43he9b8800_1.conda  1 year and 7 months ago 183 main
conda 158.7 kB | osx-64/r-allelicseries-0.0.3.0-r42he9b8800_1.conda  1 year and 7 months ago 196 main
conda 160.2 kB | linux-64/r-allelicseries-0.0.3.0-r43h08d816e_1.conda  1 year and 7 months ago 1368 main
conda 160.7 kB | linux-64/r-allelicseries-0.0.3.0-r42h08d816e_1.conda  1 year and 7 months ago 1330 main
conda 156.8 kB | win-64/r-allelicseries-0.0.3.0-r41h78deb2a_0.conda  1 year and 7 months ago 434 main
conda 158.8 kB | osx-64/r-allelicseries-0.0.3.0-r42he9b8800_0.conda  1 year and 7 months ago 181 main
conda 160.7 kB | linux-64/r-allelicseries-0.0.3.0-r42h08d816e_0.conda  1 year and 7 months ago 1328 main

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