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conda-forge / packages / r-allelicseries

Implementation of gene-level rare variant association tests targeting allelic series: genes where increasingly deleterious mutations have increasingly large phenotypic effects. The COding-variant Allelic Series Test (COAST) operates on the benign missense variants (BMVs), deleterious missense variants (DMVs), and protein truncating variants (PTVs) within a gene. COAST uses a set of adjustable weights that tailor the test towards rejecting the null hypothesis for genes where the average magnitude of effect increases monotonically from BMVs to DMVs to PTVs. See McCaw ZR, Somineni H, Bereket M, Klein C, Karaletsos T, Casale FP, Koller D, Soare TW. (2022) "An allelic series rare variant association test for candidate gene discovery" <doi:10.1101/2022.12.23.521658>.

copied from cf-post-staging / r-allelicseries
Type Size Name Uploaded Downloads Labels
conda 402.6 kB | osx-64/r-allelicseries-0.1.1.5-r45hfa0a987_1.conda  7 days and 23 hours ago 16 main
conda 400.2 kB | win-64/r-allelicseries-0.1.1.5-r44hac2c72c_1.conda  7 days and 23 hours ago 18 main
conda 406.5 kB | win-64/r-allelicseries-0.1.1.5-r45hac2c72c_1.conda  7 days and 23 hours ago 20 main
conda 396.9 kB | osx-64/r-allelicseries-0.1.1.5-r44hfa0a987_1.conda  7 days and 23 hours ago 17 main
conda 421.3 kB | linux-64/r-allelicseries-0.1.1.5-r44h3704496_1.conda  7 days and 23 hours ago 53 main
conda 427.3 kB | linux-64/r-allelicseries-0.1.1.5-r45h3704496_1.conda  7 days and 23 hours ago 48 main
conda 394.8 kB | win-64/r-allelicseries-0.1.1.5-r43hec15cfb_0.conda  5 months and 27 days ago 52 main
conda 391.1 kB | win-64/r-allelicseries-0.1.1.5-r44hec15cfb_0.conda  5 months and 27 days ago 51 main
conda 397.3 kB | osx-64/r-allelicseries-0.1.1.5-r44hda2d453_0.conda  5 months and 27 days ago 42 main
conda 396.6 kB | osx-64/r-allelicseries-0.1.1.5-r43hda2d453_0.conda  5 months and 28 days ago 39 main
conda 417.6 kB | linux-64/r-allelicseries-0.1.1.5-r43hc2d650c_0.conda  5 months and 28 days ago 455 main
conda 412.7 kB | linux-64/r-allelicseries-0.1.1.5-r44hc2d650c_0.conda  5 months and 28 days ago 460 main

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