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Provides a computational framework for analyzing mutations in immunoglobulin (Ig) sequences. Includes methods for Bayesian estimation of antigen-driven selection pressure, mutational load quantification, building of somatic hypermutation (SHM) models, and model-dependent distance calculations. Also includes empirically derived models of SHM for both mice and humans. Citations: Gupta and Vander Heiden, et al (2015) <doi:10.1093/bioinformatics/btv359>, Yaari, et al (2012) <doi:10.1093/nar/gks457>, Yaari, et al (2013) <doi:10.3389/fimmu.2013.00358>, Cui, et al (2016) <doi:10.4049/jimmunol.1502263>.

Type Size Name Uploaded Downloads Labels
conda 2.2 MB | noarch/r-shazam-1.1.2-r42h3121a25_1.tar.bz2  2 years and 18 days ago 1966 main
conda 2.2 MB | noarch/r-shazam-1.1.2-r41h3121a25_0.tar.bz2  2 years and 1 month ago 230 main
conda 2.1 MB | noarch/r-shazam-1.1.0-r41h3121a25_0.tar.bz2  2 years and 10 months ago 2136 main
conda 2.1 MB | noarch/r-shazam-0.2.3-r40h6115d3f_1.tar.bz2  4 years and 6 months ago 2551 main
conda 2.1 MB | noarch/r-shazam-0.2.3-r36h6115d3f_0.tar.bz2  4 years and 9 months ago 264 main
conda 2.1 MB | noarch/r-shazam-0.2.2-r36h6115d3f_0.tar.bz2  4 years and 11 months ago 2411 main
conda 2.1 MB | noarch/r-shazam-0.2.1-r36h6115d3f_1.tar.bz2  5 years and 29 days ago 2428 main
conda 2.1 MB | noarch/r-shazam-0.2.1-r36h6115d3f_0.tar.bz2  5 years and 3 months ago 257 main
conda 2.0 MB | osx-64/r-shazam-0.1.11-r351h6115d3f_0.tar.bz2  5 years and 7 months ago 3974 main
conda 2.0 MB | linux-64/r-shazam-0.1.11-r351h6115d3f_0.tar.bz2  5 years and 7 months ago 374 main
conda 2.0 MB | linux-64/r-shazam-0.1.10-r351h6115d3f_1.tar.bz2  5 years and 10 months ago 390 main gcc7
conda 2.0 MB | osx-64/r-shazam-0.1.10-r351h6115d3f_1.tar.bz2  5 years and 10 months ago 4086 main gcc7
conda 2.0 MB | linux-64/r-shazam-0.1.10-r351h6115d3f_0.tar.bz2  6 years and 25 days ago 314 main cf201901
conda 1.9 MB | linux-64/r-shazam-0.1.10-r341h6115d3f_0.tar.bz2  6 years and 25 days ago 446 main cf201901
conda 1.9 MB | osx-64/r-shazam-0.1.10-r341h6115d3f_0.tar.bz2  6 years and 28 days ago 213 main cf201901
conda 2.0 MB | osx-64/r-shazam-0.1.10-r351h6115d3f_0.tar.bz2  6 years and 28 days ago 109 main cf201901
conda 1.9 MB | linux-64/r-shazam-0.1.9-r3.4.1_2.tar.bz2  6 years and 6 months ago 4577 main cf201901

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