Python-first amplicon denoising — byte-identical to R's DADA2
papa2 is a complete Python port of the DADA2 amplicon denoising pipeline. All 37 R functions have Python equivalents, producing byte-identical results with no R dependency. Includes quality filtering, dereplication, error learning, denoising, paired-end merging, chimera removal, and taxonomy assignment backed by a compiled C/C++ core.
