bioconda / packages / bioconductor-spsimseq 1.4.0

Semi-parametric simulation tool for bulk and single-cell RNA sequencing data

Installers

conda install

  • noarch  v1.4.0
To install this package with conda run:
conda install -c bioconda bioconductor-spsimseq

Description

SPsimSeq uses a specially designed exponential family for density estimation to constructs the distribution of gene expression levels from a given real RNA sequencing data (single-cell or bulk), and subsequently simulates a new dataset from the estimated marginal distributions using Gaussian-copulas to retain the dependence between genes. It allows simulation of multiple groups and batches with any required sample size and library size.


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