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bioconductor-sparsedossa

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Sparse Data Observations for Simulating Synthetic Abundance

Installation

To install this package, run one of the following:

Conda
$conda install bioconda::bioconductor-sparsedossa

Usage Tracking

1.24.0
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Downloads (Last 6 months): 0

Description

The package is to provide a model based Bayesian method to characterize and simulate microbiome data. sparseDOSSA's model captures the marginal distribution of each microbial feature as a truncated, zero-inflated log-normal distribution, with parameters distributed as a parent log-normal distribution. The model can be effectively fit to reference microbial datasets in order to parameterize their microbes and communities, or to simulate synthetic datasets of similar population structure. Most importantly, it allows users to include both known feature-feature and feature-metadata correlation structures and thus provides a gold standard to enable benchmarking of statistical methods for metagenomic data analysis.

About

Summary

Sparse Data Observations for Simulating Synthetic Abundance

Last Updated

Jul 7, 2023 at 08:33

License

MIT + file LICENSE

Total Downloads

22.4K

Supported Platforms

noarch