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bioconductor-scbfa

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A dimensionality reduction tool using gene detection pattern to mitigate noisy expression profile of scRNA-seq

Installation

To install this package, run one of the following:

Conda
$conda install bioconda::bioconductor-scbfa

Usage Tracking

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Description

This package is designed to model gene detection pattern of scRNA-seq through a binary factor analysis model. This model allows user to pass into a cell level covariate matrix X and gene level covariate matrix Q to account for nuisance variance(e.g batch effect), and it will output a low dimensional embedding matrix for downstream analysis.

About

Summary

A dimensionality reduction tool using gene detection pattern to mitigate noisy expression profile of scRNA-seq

Last Updated

Dec 30, 2024 at 14:06

License

GPL-3 + file LICENSE

Total Downloads

18.7K

Supported Platforms

noarch