bioconda / packages / bioconductor-river 1.18.0

R package for RIVER (RNA-Informed Variant Effect on Regulation)

Installers

Info: This package contains files in non-standard labels.

conda install

  • noarch  v1.18.0
To install this package with conda run one of the following:
conda install -c bioconda bioconductor-river
conda install -c bioconda/label/gcc7 bioconductor-river

Description

An implementation of a probabilistic modeling framework that jointly analyzes personal genome and transcriptome data to estimate the probability that a variant has regulatory impact in that individual. It is based on a generative model that assumes that genomic annotations, such as the location of a variant with respect to regulatory elements, determine the prior probability that variant is a functional regulatory variant, which is an unobserved variable. The functional regulatory variant status then influences whether nearby genes are likely to display outlier levels of gene expression in that person. See the RIVER website for more information, documentation and examples.


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