bioconda / packages / bioconductor-puma 3.30.0

Propagating Uncertainty in Microarray Analysis(including Affymetrix tranditional 3' arrays and exon arrays and Human Transcriptome Array 2.0)


Info: This package contains files in non-standard labels.

conda install

  • linux-64  v3.30.0
  • osx-64  v3.30.0
To install this package with conda run one of the following:
conda install -c bioconda bioconductor-puma
conda install -c bioconda/label/gcc7 bioconductor-puma
conda install -c bioconda/label/cf201901 bioconductor-puma


Most analyses of Affymetrix GeneChip data (including tranditional 3' arrays and exon arrays and Human Transcriptome Array 2.0) are based on point estimates of expression levels and ignore the uncertainty of such estimates. By propagating uncertainty to downstream analyses we can improve results from microarray analyses. For the first time, the puma package makes a suite of uncertainty propagation methods available to a general audience. In additon to calculte gene expression from Affymetrix 3' arrays, puma also provides methods to process exon arrays and produces gene and isoform expression for alternative splicing study. puma also offers improvements in terms of scope and speed of execution over previously available uncertainty propagation methods. Included are summarisation, differential expression detection, clustering and PCA methods, together with useful plotting functions.

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