bioconda / packages / bioconductor-hicrep 1.8.0

Hi-C is a powerful technology for studying genome-wide chromatin interactions. However, current methods for assessing Hi-C data reproducibility can produce misleading results because they ignore spatial features in Hi-C data, such as domain structure and distance-dependence. We present a novel reproducibility measure that systematically takes these features into consideration. This measure can assess pairwise differences between Hi-C matrices under a wide range of settings, and can be used to determine optimal sequencing depth. Compared to existing approaches, it consistently shows higher accuracy in distinguishing subtle differences in reproducibility and depicting interrelationships of cell lineages than existing approaches. This R package `hicrep` implements our approach.

Installers

Info: This package contains files in non-standard labels.

conda install

  • linux-64  v1.4.0
  • osx-64  v1.4.0
  • noarch  v1.8.0
To install this package with conda run one of the following:
conda install -c bioconda bioconductor-hicrep
conda install -c bioconda/label/gcc7 bioconductor-hicrep
conda install -c bioconda/label/cf201901 bioconductor-hicrep

Description

PRIVACY POLICY  |  EULA (Anaconda Cloud v2.33.29) © 2019 Anaconda, Inc. All Rights Reserved.