bioconda / packages / bioconductor-hicdcplus 1.0.0

Hi-C Direct Caller Plus

Installers

conda install

  • linux-64  v1.0.0
  • osx-64  v1.0.0
To install this package with conda run:
conda install -c bioconda bioconductor-hicdcplus

Description

Systematic 3D interaction calls and differential analysis for Hi-C and HiChIP. The HiC-DC+ (Hi-C/HiChIP direct caller plus) package enables principled statistical analysis of Hi-C and HiChIP data sets – including calling significant interactions within a single experiment and performing differential analysis between conditions given replicate experiments – to facilitate global integrative studies. HiC-DC+ estimates significant interactions in a Hi-C or HiChIP experiment directly from the raw contact matrix for each chromosome up to a specified genomic distance, binned by uniform genomic intervals or restriction enzyme fragments, by training a background model to account for random polymer ligation and systematic sources of read count variation.


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