bioconda / packages / bioconductor-desingle 1.8.0

DEsingle for detecting three types of differential expression in single-cell RNA-seq data


Info: This package contains files in non-standard labels.

conda install

  • noarch  v1.8.0
To install this package with conda run one of the following:
conda install -c bioconda bioconductor-desingle
conda install -c bioconda/label/gcc7 bioconductor-desingle


DEsingle is an R package for differential expression (DE) analysis of single-cell RNA-seq (scRNA-seq) data. It defines and detects 3 types of differentially expressed genes between two groups of single cells, with regard to different expression status (DEs), differential expression abundance (DEa), and general differential expression (DEg). DEsingle employs Zero-Inflated Negative Binomial model to estimate the proportion of real and dropout zeros and to define and detect the 3 types of DE genes. Results showed that DEsingle outperforms existing methods for scRNA-seq DE analysis, and can reveal different types of DE genes that are enriched in different biological functions.

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