bioconda / packages / bioconductor-deqms 1.6.0

a tool to perform statistical analysis of differential protein expression for quantitative proteomics data.

Installers

Info: This package contains files in non-standard labels.

conda install

  • linux-64  v1.0.1
  • noarch  v1.6.0
  • osx-64  v1.0.1
To install this package with conda run one of the following:
conda install -c bioconda bioconductor-deqms
conda install -c bioconda/label/gcc7 bioconductor-deqms
conda install -c bioconda/label/cf201901 bioconductor-deqms

Description

DEqMS is developped on top of Limma. However, Limma assumes same prior variance for all genes. In proteomics, the accuracy of protein abundance estimates varies by the number of peptides/PSMs quantified in both label-free and labelled data. Proteins quantification by multiple peptides or PSMs are more accurate. DEqMS package is able to estimate different prior variances for proteins quantified by different number of PSMs/peptides, therefore acchieving better accuracy. The package can be applied to analyze both label-free and labelled proteomics data.

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