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bioconductor-dar

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Differential Abundance Analysis by Consensus

Installation

To install this package, run one of the following:

Conda
$conda install bioconda::bioconductor-dar

Usage Tracking

1.2.0
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Downloads (Last 6 months): 0

Description

Differential abundance testing in microbiome data challenges both parametric and non-parametric statistical methods, due to its sparsity, high variability and compositional nature. Microbiome-specific statistical methods often assume classical distribution models or take into account compositional specifics. These produce results that range within the specificity vs sensitivity space in such a way that type I and type II error that are difficult to ascertain in real microbiome data when a single method is used. Recently, a consensus approach based on multiple differential abundance (DA) methods was recently suggested in order to increase robustness. With dar, you can use dplyr-like pipeable sequences of DA methods and then apply different consensus strategies. In this way we can obtain more reliable results in a fast, consistent and reproducible way.

About

Summary

Differential Abundance Analysis by Consensus

Last Updated

Dec 25, 2024 at 07:06

License

MIT + file LICENSE

Total Downloads

329

Supported Platforms

noarch