bioconda / packages / bioconductor-crisprseek 1.32.0

Design of target-specific guide RNAs in CRISPR-Cas9, genome-editing systems


Info: This package contains files in non-standard labels.

conda install

  • linux-64  v1.20.0
  • osx-64  v1.20.0
  • noarch  v1.32.0
To install this package with conda run one of the following:
conda install -c bioconda bioconductor-crisprseek
conda install -c bioconda/label/gcc7 bioconductor-crisprseek
conda install -c bioconda/label/cf201901 bioconductor-crisprseek


The package includes functions to find potential guide RNAs for the CRISPR editing system including Base Editors and the Prime Editor for input target sequences, optionally filter guide RNAs without restriction enzyme cut site, or without paired guide RNAs, genome-wide search for off-targets, score, rank, fetch flank sequence and indicate whether the target and off-targets are located in exon region or not. Potential guide RNAs are annotated with total score of the top5 and topN off-targets, detailed topN mismatch sites, restriction enzyme cut sites, and paired guide RNAs. The package also output indels and their frequencies for Cas9 targeted sites.

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