bioconductor-cpvsnp
Gene set analysis methods for SNP association p-values that lie in genes in given gene sets
Gene set analysis methods for SNP association p-values that lie in genes in given gene sets
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Gene set analysis methods exist to combine SNP-level association p-values into gene sets, calculating a single association p-value for each gene set. This package implements two such methods that require only the calculated SNP p-values, the gene set(s) of interest, and a correlation matrix (if desired). One method (GLOSSI) requires independent SNPs and the other (VEGAS) can take into account correlation (LD) among the SNPs. Built-in plotting functions are available to help users visualize results.
Summary
Gene set analysis methods for SNP association p-values that lie in genes in given gene sets
Last Updated
Dec 28, 2024 at 16:42
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Artistic-2.0
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