bioconda / packages / bioconductor-clipper 1.32.0

Gene Set Analysis Exploiting Pathway Topology

Installers

Info: This package contains files in non-standard labels.

conda install

  • linux-64  v1.32.0
  • osx-64  v1.32.0
To install this package with conda run one of the following:
conda install -c bioconda bioconductor-clipper
conda install -c bioconda/label/gcc7 bioconductor-clipper

Description

Implements topological gene set analysis using a two-step empirical approach. It exploits graph decomposition theory to create a junction tree and reconstruct the most relevant signal path. In the first step clipper selects significant pathways according to statistical tests on the means and the concentration matrices of the graphs derived from pathway topologies. Then, it "clips" the whole pathway identifying the signal paths having the greatest association with a specific phenotype.


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