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bioconductor-cleanupdtseq

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cleanUpdTSeq cleans up artifacts from polyadenylation sites from oligo(dT)-mediated 3' end RNA sequending data

Installation

To install this package, run one of the following:

Conda
$conda install bioconda::bioconductor-cleanupdtseq

Usage Tracking

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Description

This package implements a Naive Bayes classifier for accurately differentiating true polyadenylation sites (pA sites) from oligo(dT)-mediated 3' end sequencing such as PAS-Seq, PolyA-Seq and RNA-Seq by filtering out false polyadenylation sites, mainly due to oligo(dT)-mediated internal priming during reverse transcription. The classifer is highly accurate and outperforms other heuristic methods.

About

Summary

cleanUpdTSeq cleans up artifacts from polyadenylation sites from oligo(dT)-mediated 3' end RNA sequending data

Last Updated

Dec 31, 2024 at 04:17

License

GPL-2

Total Downloads

34.5K

Supported Platforms

noarch

Unsupported Platforms

linux-64 Last supported version: 1.18.0
macOS-64 Last supported version: 1.18.0