CMD + K

bioconductor-ccimpute

Community

ccImpute: an accurate and scalable consensus clustering based approach to impute dropout events in the single-cell RNA-seq data (https://doi.org/10.1186/s12859-022-04814-8)

Installation

To install this package, run one of the following:

Conda
$conda install bioconda::bioconductor-ccimpute

Usage Tracking

1.8.0
1.4.0
1.2.1
1.0.0
4 / 8 versions selected
Downloads (Last 6 months): 0

Description

Dropout events make the lowly expressed genes indistinguishable from true zero expression and different than the low expression present in cells of the same type. This issue makes any subsequent downstream analysis difficult. ccImpute is an imputation algorithm that uses cell similarity established by consensus clustering to impute the most probable dropout events in the scRNA-seq datasets. ccImpute demonstrated performance which exceeds the performance of existing imputation approaches while introducing the least amount of new noise as measured by clustering performance characteristics on datasets with known cell identities.

About

Summary

ccImpute: an accurate and scalable consensus clustering based approach to impute dropout events in the single-cell RNA-seq data (https://doi.org/10.1186/s12859-022-04814-8)

Last Updated

Dec 21, 2024 at 23:44

License

GPL-3

Total Downloads

4.4K

Supported Platforms

linux-64
macOS-64