bioconda / packages / bioconductor-catalyst 1.12.1

Cytometry dATa anALYSis Tools

Installers

Info: This package contains files in non-standard labels.

conda install

  • noarch  v1.12.1
To install this package with conda run one of the following:
conda install -c bioconda bioconductor-catalyst
conda install -c bioconda/label/gcc7 bioconductor-catalyst

Description

Mass cytometry (CyTOF) uses heavy metal isotopes rather than fluorescent tags as reporters to label antibodies, thereby substantially decreasing spectral overlap and allowing for examination of over 50 parameters at the single cell level. While spectral overlap is significantly less pronounced in CyTOF than flow cytometry, spillover due to detection sensitivity, isotopic impurities, and oxide formation can impede data interpretability. We designed CATALYST (Cytometry dATa anALYSis Tools) to provide a pipeline for preprocessing of cytometry data, including i) normalization using bead standards, ii) single-cell deconvolution, and iii) bead-based compensation.

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