bioconductor-bionet
Routines for the functional analysis of biological networks
Routines for the functional analysis of biological networks
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This package provides functions for the integrated analysis of protein-protein interaction networks and the detection of functional modules. Different datasets can be integrated into the network by assigning p-values of statistical tests to the nodes of the network. E.g. p-values obtained from the differential expression of the genes from an Affymetrix array are assigned to the nodes of the network. By fitting a beta-uniform mixture model and calculating scores from the p-values, overall scores of network regions can be calculated and an integer linear programming algorithm identifies the maximum scoring subnetwork.
Summary
Routines for the functional analysis of biological networks
Last Updated
Feb 28, 2026 at 23:47
License
GPL (>= 2)
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