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bioconda / packages / bioconductor-bifet 1.22.0

Bias-free Footprint Enrichment Test

Installers

Info: This package contains files in non-standard labels.
  • noarch v1.22.0

conda install

To install this package run one of the following:
conda install bioconda::bioconductor-bifet
conda install bioconda/label/gcc7::bioconductor-bifet

Description

BiFET identifies TFs whose footprints are over-represented in target regions compared to background regions after correcting for the bias arising from the imbalance in read counts and GC contents between the target and background regions. For a given TF k, BiFET tests the null hypothesis that the target regions have the same probability of having footprints for the TF k as the background regions while correcting for the read count and GC content bias. For this, we use the number of target regions with footprints for TF k, tk as a test statistic and calculate the p-value as the probability of observing tk or more target regions with footprints under the null hypothesis.


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