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bioconda / packages / bioconductor-awst 1.10.0

Asymmetric Within-Sample Transformation

Installers

  • noarch v1.10.0

conda install

To install this package run one of the following:
conda install bioconda::bioconductor-awst

Description

We propose an Asymmetric Within-Sample Transformation (AWST) to regularize RNA-seq read counts and reduce the effect of noise on the classification of samples. AWST comprises two main steps: standardization and smoothing. These steps transform gene expression data to reduce the noise of the lowly expressed features, which suffer from background effects and low signal-to-noise ratio, and the influence of the highly expressed features, which may be the result of amplification bias and other experimental artifacts.


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