SaTScan(TM) (http://www.satscan.org) is software for finding regions in Time, Space, or Time-Space that have excess risk, based on scan statistics, and uses Monte Carlo hypothesis testing to generate P-values for these regions. The rsatscan package provides functions for writing R data frames in SaTScan-readable formats, for setting SaTScan parameters, for running SaTScan in the OS, and for reading the files that SaTScan creates.