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Provides the functions for planning and conducting a clinical trial with adaptive sample size determination. Maximal statistical efficiency will be exploited even when dramatic or multiple adaptations are made. Such a trial consists of adaptive determination of sample size at an interim analysis and implementation of frequentist statistical test at the interim and final analysis with a prefixed significance level. The required assumptions for the stage-wise test statistics are independent and stationary increments and normality. Predetermination of adaptation rule is not required.

Type Size Name Uploaded Downloads Labels
conda 175.3 kB | linux-64/r-adpss-0.1.1-r42h884c59f_0.tar.bz2  2 years and 8 months ago 62 main
conda 181.9 kB | win-64/r-adpss-0.1.1-r36h796a38f_0.tar.bz2  4 years and 11 months ago 60 main
conda 176.1 kB | osx-64/r-adpss-0.1.1-r36h466af19_0.tar.bz2  4 years and 11 months ago 25 main
conda 175.0 kB | linux-64/r-adpss-0.1.1-r36h29659fb_0.tar.bz2  4 years and 11 months ago 62 main

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