Uses an indirect method based on truncated quantile-quantile plots to estimate reference limits from routine laboratory data. The principle of the method was developed by Robert G Hoffmann (1963) <doi:10.1001/jama.1963.03060110068020> and modified by Georg Hoffmann and colleagues (2015) <doi:10.1515/labmed-2015-0104>, (2020) <doi:10.1515/labmed-2020-0005>, and (2022) <doi:10.1007/978-3-031-15509-3_31>.
