Pymrio is an open source tool for analysing global environmentally extended multi-regional input-output tables (EE MRIOs). Pymrio aims to provide a high-level abstraction layer for global EE MRIO databases in order to simplify common EE MRIO data tasks. Pymrio includes automatic download functions and parsers for available EE MRIO databases like EXIOBASE, WIOD and EORA26. It automatically checks parsed EE MRIOs for missing data necessary for calculating standard EE MRIO accounts (such as footprint, territorial, impacts embodied in trade) and calculates all missing tables. Various data report and visualization methods help to explore the dataset by comparing the different accounts across countries.