bioconductor-scbfa
A dimensionality reduction tool using gene detection pattern to mitigate noisy expression profile of scRNA-seq
A dimensionality reduction tool using gene detection pattern to mitigate noisy expression profile of scRNA-seq
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This package is designed to model gene detection pattern of scRNA-seq through a binary factor analysis model. This model allows user to pass into a cell level covariate matrix X and gene level covariate matrix Q to account for nuisance variance(e.g batch effect), and it will output a low dimensional embedding matrix for downstream analysis.
Summary
A dimensionality reduction tool using gene detection pattern to mitigate noisy expression profile of scRNA-seq
Last Updated
Dec 30, 2024 at 14:06
License
GPL-3 + file LICENSE
Total Downloads
18.7K
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