bioconductor-msstatslobd
Assay characterization: estimation of limit of blanc(LoB) and limit of detection(LOD)
Assay characterization: estimation of limit of blanc(LoB) and limit of detection(LOD)
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The MSstatsLOBD package allows calculation and visualization of limit of blac (LOB) and limit of detection (LOD). We define the LOB as the highest apparent concentration of a peptide expected when replicates of a blank sample containing no peptides are measured. The LOD is defined as the measured concentration value for which the probability of falsely claiming the absence of a peptide in the sample is 0.05, given a probability 0.05 of falsely claiming its presence. These functionalities were previously a part of the MSstats package. The methodology is described in Galitzine (2018) .
Summary
Assay characterization: estimation of limit of blanc(LoB) and limit of detection(LOD)
Last Updated
Dec 14, 2024 at 15:20
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Artistic-2.0
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