Fit a 2-parameter continual reassessment method (CRM) model (O'Quigley and Shen (1996), <doi: 10.2307/2532905>) regularized with L2 norm (Friedman et al. (2010), <doi: 10.18637/jss.v033.i01>) adjusted by the distance with the target dose limiting toxicity (DLT) rate.
