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genomedk / packages

Package Name Access Summary Updated
r-diversitree public Contains a number of comparative 'phylogenetic' methods, mostly focusing on analysing diversification and character evolution. Contains implementations of 'BiSSE' (Binary State 'Speciation' and Extinction) and its unresolved tree extensions, 'MuSSE' (Multiple State 'Speciation' and Extinction), 'QuaSSE', 'GeoSSE', and 'BiSSE-ness' Other included methods include Markov models of discrete and continuous trait evolution and constant rate 'speciation' and extinction. 2025-03-25
psmc public Pairwise Sequentially Markovian Coalescent 2025-03-25
snoreport public SnoReport 2.0: new features and a refined Support Vector Machine to improve snoRNA identification 2025-03-25
stacks public Stacks is a software pipeline for building loci from RAD-seq 2025-03-25
r-lava-jw public Melds genome-wide association tests with structural equation modeling (SEM) using 'OpenMx'. This package contains low-level C/C++ code to rapidly read genetic data encoded in U.K. Biobank or 'plink' formats. Prebuilt modeling options include one and two factor models. Alternately, analyses may utilize arbitrary, user-provided SEMs. See Verhulst, Maes, & Neale (2017) <doi:10.1007/s10519-017-9842-6> for details. An updated manuscript is in preparation. 2025-03-25
r-matrixsampling public Provides samplers for various matrix variate distributions: Wishart, inverse-Wishart, normal, t, inverted-t, Beta type I, Beta type II, Gamma, confluent hypergeometric. Allows to simulate the noncentral Wishart distribution without the integer restriction on the degrees of freedom. 2025-03-25
r-superfreq public SuperFreq analyses SNVs and CNAs of multiple cancer exomes, sharing all information across samples and mutation types. The inputs are the bam-files and a preliminary SNV calling in .vcf format. SuperFreq filters and annotates the SNVs, calls CNAs and tracks clones over samples from the same individual. A matched normal improves results, but is not necessary. SuperFreq requireas at least two (preferably 5-10 or more) reference normal samples that do not have to be related to the studied cancer samples, but must be from the same sequencing platform and capture. These are used to improve results through variance of read depth and requrring false SNVs amongst other things. SuperFreq produces ample output in terms of plots and spread sheets, both for identifying properties of the cancer samples and for quality control. 2025-03-25
r-gwsem public Melds genome-wide association tests with structural equation modeling (SEM) using 'OpenMx'. This package contains low-level C/C++ code to rapidly read genetic data encoded in U.K. Biobank or 'plink' formats. Prebuilt modeling options include one and two factor models. Alternately, analyses may utilize arbitrary, user-provided SEMs. See Verhulst, Maes, & Neale (2017) <doi:10.1007/s10519-017-9842-6> for details. An updated manuscript is in preparation. 2025-03-25
seq-lang public A strongly-typed and statically-compiled high-performance Pythonic language! 2025-03-25
r-diem public Identification of debris-containing droplets from a droplet-based single cell/nucleus RNA-seq. 'diem' classifies droplets by modeling droplet expression with a multinomial mixture model. Droplets are assigned to debris or cell type clusters after estimating parameters with expectation maximization (EM). Provides quantifications of contamination in individual droplets for filtering and use as a covariate. See Alvarez M, Rahmani E, et al (2019) <doi:10.1101/786285> for details. 2025-03-25
tinytex public A lightweight LaTeX distribution based on TeX Live 2025-03-25
treepl public Phylogenetic penalized likelihood 2025-03-25
rnahybrid public RNAhybrid is a tool for finding the minimum free energy hybridization of a long and a short RNA. 2025-03-25
primer3 public Design PCR primers from DNA sequence. From mispriming libraries to sequence quality data to the generation of internal oligos, primer3 does it. 2025-03-25
exabayes public ExaBayes is a software package for Bayesian tree inference. It is particularly suitable for large-scale analyses on computer clusters. 2025-03-25
fdstools public Forensic DNA Sequencing Tools 2025-03-25
phyx public No Summary 2025-03-25
epacts public No Summary 2025-03-25
regenie public whole genome regression modelling of large genome-wide association studies 2025-03-25
singularity public Singularity: Application containers for Linux 2025-03-25
grapes-static public Rate of Adaptive Protein Evolution Software 2025-03-25
argweaver public Sampling and manipulating genome-wide ancestral recombination graphs (ARGs) 2025-03-25
maffilter public The MafFilter genome alignment processor 2025-03-25
phusion2-crossgenome public No Summary 2025-03-25
redundans public No Summary 2025-03-25

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