SuperIso is a program for calculation of flavour physics observables in the Standard Model (SM), general two-Higgs-doublet model (2HDM), minimal supersymmetric Standard Model (MSSM) and next to minimal supersymmetric Standard Model (NMSSM). SuperIso incorporates many flavour observables such as the branching ratio of B → Xs,d γ at NNLO, the isospin asymmetry of B → K* γ, the branching ratio of Bs,d → μ+ μ-, the branching ratio of B → τ ν, the branching ratio of B → D τ ν, the branching ratios of K → μ ν, K → μ μ , K → π ν ν̄, K → π l+ l-, as well as the branching ratios of Ds → τ ν and Ds → μ ν, Λb → Λ l+ l-, and the branching rations and angular observables related to the B → Xs l+ l- and B → K(*) l+ l- decays. It also computes the muon anomalous magnetic moment (g-2).