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Linear Mixed effect Model Splines ('lmms') implements linear mixed effect model splines for modelling and differential expression for highly dimensional data sets: investNoise() for quality control and filterNoise() for removing non-informative trajectories; lmmSpline() to model time course expression profiles and lmmsDE() performs differential expression analysis to identify differential expression between groups, time and/or group x time interaction.

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Summary

Linear Mixed effect Model Splines ('lmms') implements linear mixed effect model splines for modelling and differential expression for highly dimensional data sets: investNoise() for quality control and filterNoise() for removing non-informative trajectories; lmmSpline() to model time course expression profiles and lmmsDE() performs differential expression analysis to identify differential expression between groups, time and/or group x time interaction.

Last Updated

Sep 22, 2025 at 06:15

License

GPL-2.0-only