Protein-ligand interactions are foundational to the understanding of science and discovery of therapies. However, to this date, no large, high quality datasets with real-life relevant evaluations exist.

PLINDER is an academic-industry collaboration to address this, driven by VantAI, NVIDIA, the Computational Structural Biology group at the University of Basel & SIB Swiss Institute of Bioinformatics - co-organizers of CASP, and MIT. We aim to provide a gold standard dataset and evaluations to push the field of computational protein-ligand interactions prediction forward.