bioconductor-targetscore
TargetScore: Infer microRNA targets using microRNA-overexpression data and sequence information
TargetScore: Infer microRNA targets using microRNA-overexpression data and sequence information
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Infer the posterior distributions of microRNA targets by probabilistically modelling the likelihood microRNA-overexpression fold-changes and sequence-based scores. Variaitonal Bayesian Gaussian mixture model (VB-GMM) is applied to log fold-changes and sequence scores to obtain the posteriors of latent variable being the miRNA targets. The final targetScore is computed as the sigmoid-transformed fold-change weighted by the averaged posteriors of target components over all of the features.
Summary
TargetScore: Infer microRNA targets using microRNA-overexpression data and sequence information
Information Last Updated
Apr 22, 2025 at 15:28
License
GPL-2
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41.3K
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