bioconda / packages / bioconductor-synlet 1.18.0

Hits Selection for Synthetic Lethal RNAi Screen Data

Installers

Info: This package contains files in non-standard labels.

conda install

  • linux-64  v1.10.0
  • osx-64  v1.10.0
  • noarch  v1.18.0
To install this package with conda run one of the following:
conda install -c bioconda bioconductor-synlet
conda install -c bioconda/label/gcc7 bioconductor-synlet
conda install -c bioconda/label/cf201901 bioconductor-synlet

Description

Select hits from synthetic lethal RNAi screen data. For example, there are two identical celllines except one gene is knocked-down in one cellline. The interest is to find genes that lead to stronger lethal effect when they are knocked-down further by siRNA. Quality control and various visualisation tools are implemented. Four different algorithms could be used to pick up the interesting hits. This package is designed based on 384 wells plates, but may apply to other platforms with proper configuration.

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